教师名录
汪海燕,专职副研究员/硕士生导师
主要研究方向:
1.生物芯片制备,包括基于微米和纳米级生物传感界面的新型生物芯片设计、开发、制备和测试。
2.微纳传感,包手微纳流体设计和动力学模型构建。
3.精准诊疗芯片开发,针对“卡脖子”问题,面向临床需求开发快速诊断核心技术。
4. 蛋白质测序技术,包括纳米孔单分子测序技术的开发和控制技术。
科研方面:
近年来发表论文22篇,授权专利1项。包括主要包括Chem. Commun.、Anal. Chem.和ACS Sensor.等 担任Result in Chemistry的专刊编辑和多个学术期刊的审稿专家,包括专业领域一区期刊Chemical Science和ACS Sensors。
2019.12-至今 云顶集团 云顶集团 专职副研究员
2015.02- 2019.10 美国国家标准与技术研究所 Guest Researhcer
Chemical Science
ACS Sensors
Guest Editor of Results in Chemistry
2013.10 华东理工大学“研究生国家奖学金”
2013.04 华东理工大学“2013年度优秀博士毕业生”
2012.10 华东理工大学“优秀员工干部”
2012.10 华东理工大学“优秀社会工作奖一等奖”
2011.12 华东理工大学“高水平论文奖”
2010.10 华东理工大学计划外奖学金:天鼎东岳一等奖
1. LiuW., Yao X., Zhu W., Wang J., Zhou F., Qian X., Tiemuer A., Yang S., Wang Hai-Yan*,Liu Y., Azo-Based Hypoxia-Responsive Self-Assembly Near-Infrared FluorescentNanoprobe for In Vivo Real-Time Bioimaging of Tumors. ACS Appl. Bio Mater.2021, 4, 3, 2752–2758
2. Hui Yu, Wanlu Sun, Aliya Tiemuer, Yuanyuan Zhang, Hai-YanWang,* Yi Liu,*Mitochondria targeted near-infrared chemodosimeter for upconversionluminescence bioimaging of hypoxia.Chem. Commun., 2021,57, 5207-5210
3. Xiaoli Qian, Wenchao Zhu, Hui Yu, Yue Xu, WangwangLiu, Hai-Yan Wang*, Yi Liu, Mitochondria-targeted near-infrared fluorescent probe for monitoring of a Copper(I) in living cellsand In vivo,Dyes and Pigments, 2021, 194,109561.
4. W Zhu, X Qian, J Wang, H Yu, W Liu, Hai-Yan Wang*,Y Liu, Near-infrared frequency upconversion probes for monitoring glutathioneS-transferase to evaluate acute liver injury. Sensors and Actuators B:Chemical. 2021, 347, 130640.
5. W Zhu, H Yu, X Qian, KLu, C Zhao, Y Zhang, Hai-Yan Wang*, Y Liu, Near-infrared frequency upconversion probe for revealing therelationship between glutathione S-transferase and drug-resistance. AnalyticaChimica Acta. 2021, 1181, 338920
6. Wang H.-Y., Kasianowicz J. J., Robertson,J.W.F., Poster L. D., and Ettedgui, J.,A Comparison of Ion Channel Current Blockades Caused by Individual Poly(ethylene glycol) Molecules and Polyoxometalate Nanoclusters. TheEuropean Physical Journal E.2019,42 (6),83.
7. WangH.-Y., Zhang H., Chen S.,Liu Y. Fluorescein-Inspired Near-Infrared Chemodosimeter for LuminescenceBioimaging. Current medicinal chemistry2019, 26 (21), 4029-4041
8. Wang H.-Y., Ettedgui, J., Forstater, J.H., Robertson,J.W.F.,Reiner J. E., Zhang H., Chen S., Kasianowicz,J.J. Determining the physical properties of molecules with nanometer-scalepores. ACS Sensors2018, 3,251-263.
9. Liu Y.,Yao X.-F. & Wang H.-Y.*, ProteinDetection Though Single Molecule Nanopore. ChineseJournal of Analytical Chemistry2018, 46, Issue 6, e1838-e1846.
10. Wang, H.-Y., Song, Z.-Y., Zhang, H.-S.,& Chen, S.-P. Single-molecule analysis of lead (II)-binding aptamer conformationalchanges in an α-hemolysin nanopore, and sensitive detection of lead (II). Microchimica Acta2016, 183,1003-1010.
11. Wang, H.-Y., Gu, Z., Wang,J., & Long, Y.-T. Analysis of a single α-synuclein fibrillation by theinteraction with a protein nanopore. AnalyticalChemistry 2013, 85, 8254-8261.
12. Wang, H.-Y.,Li, Y., Qin, L.-X., Heyman, A., Shoseyov, O., Willner, I., Long, Y.-T., &Tian, H. Single-molecule DNA detection using a novel SP1 protein nanopore. Chemical Communications 2013, 49, 1741-1743.
13. Wang,H.-Y.,Ying, Y.-L., Li, Y., Kraatz, H.B., & Long, Y.-T. Nanopore analysis ofβ-amyloid peptide aggregation transition induced by small molecules. Analytical Chemistry 2011, 83, 1746-1752.
14. Wang,H.-Y.,Ying, Y.-L., Li, Y., & Long, Y.-T. Peering into Biological Nanopore: APractical Technology to Single‐Molecule Analysis. Chemistry: An Asian Journal 2011, 5, 952-1961.
2020.01-2020.12, 项目主持人,中央高校基本业务费基础科研扶持项目-理工类:基于纳米孔的生物仿生界面机械性能研究(2242020K40221)
2014.09-2016.12, 项目主持人, 中国博士后科学基金第56批一等资助项目:纳米通道用于核酸适配体单分子识别行为研究(2014M560670)
2021.01-2024.12 项目参与人,国家自然科学基金面上项目:固态纳米孔核酸检测的关键技术和机理 (52075099)
2008.12-2011.12,项目主要研究人员,国家自然科学基金面上项目:基于alpha-溶血素纳米孔的淀粉样β肽单分子分析(No. 20875030)
2008.09- 2011.02,项目主要研究人员,上海市教育委员会曙光计划项目:基于纳米通道的老年痴呆症蛋白的单分子分析(No. 07SG36)
喻皓,汪海燕,龙亿涛等基于LabVIEW的纳米通道单分子检测系统,授权专利号:ZL 2010 2 0169643.6